Tag Archives: alzheimer’s

Some Medications May Help to Cut Risk of Alzheimer’s Disease

A recent report indicates aspirin and non-steroidal antinflammatory drugs seem to have the positive and perhaps unexpected benefit, of cutting a person’s risk of developing AD.

Researchers at John’s Hopkins reviewed data from 13,499 cases to measure the protective effect from these commonly used drugs on AD risk. Over the course of the studies 820 people developed AD. However, those who used the non-steroidal drugs including aspirin, Ibuprofen (Advil, Motrin and other brands) and Naproxen together had a 23% lower risk for AD than those who did not use such medications.

Researchers stated that while the different types of medications have different properties, they seemed to deliver the same level of protection. This study and others in the past underscore the probable contribution of an inflammatory process related to AD.

This study and the others do not suggest everyone should start taking these medications, but it might be a good topic to discuss with your doctor.

German Scientists Test New Way to Combat Alzheimer’s

German scientists have found success in reversing the plaque buildup in brains of mice. The plaque deposits are one of the hallmark features of Alzheimer’s disease (AD) and this finding may lead to viable treatments for humans.

The compound reportedly effectively blocks an enzyme responsible for development of the plaque. The compound attaches itself at the precise site on the cell wall where the toxic action occurs.

When injected directly into the brains of mice, scientists indicate the compound works well. The next step is to determine if the compound can cross the blood brain barrier, the protective shield around the brain. Animal tests have begun to determine if medicines given by mouth or injection have the high rate of efficacy as direct injection into the brain where there was a 50% reduction in plaque formation within four hours. Scientists believe that if the testing on animals goes well a human version could be available in five to ten years.

Alzheimer’s Disease in the United States

A leading cause of brain disease in the United States is Alzheimer’s disease (AD). Named after Dr. Alzheimer who published a paper in 1907 describing the cognitive and functional decline of a female patient, this disease now affects nearly 5 million people. It is estimated that those affected by AD will triple by 2050.

AD is the leading cause of progressive dementia. The disease typically erodes memory, spatial functions, language, personality and functional ability. The course of the disease approximates 10-12 years and those over the age of 85 are most at risk. Additional risk factors include female gender, family history of dementia, mood disorder, diabetes, and stroke. The cause is not known and there are no known cures or prevention.

Treatments exist to help reduce the impact of particular symptoms and early detection has advanced significantly. New treatments are being researched and these should be to market in the near future. Lifestyle for brain health has also generated new attention and interest. One aspect of a brain health lifestyle is mental stimulation, a primary function of FitBrains.

If your loved one is experiencing memory loss and there is some concern about this change it is advised that he or she receive a comprehensive dementia examination. This will help to discern if the memory and other cognitive changes fall outside the range of normal and if dementia is present. Early detection is important because existing treatments can be started.

What is Dementia?

Dementia is a clinical term used to describe loss of general intelligence, forgetfulness, language or other cognitive disturbance, personality change, and functional decline. There are nearly 70 or more causes of dementia, with the most common cause attributed to Alzheimer’s disease (AD). Other common causes of dementia include Vascular dementia (VaD), Lewy Body Dementia, Alcohol and substance based dementia, Huntington’s disease, Parkinson’s disease, depression, head injury, seizure disorder and many others.

Most causes of dementia are irreversible meaning the dementia will not be cured or get better. Only 3-5% of dementias are considered reversible. Examples of reversible dementia include B-12 deficiency, depression, and thyroid disorder. Alzheimer’s disease, the leading type of irreversible dementia affects those primarily over the age of 65. There is no know cause of AD nor is there any cure at this time.

Medications exist to treat the symptoms of dementia without actually stopping the underlying disease process. Often persons with dementia can become depressed, anxious, or even psychotic. These co-morbid conditions can be effectively treated with psychotropic medication, structure and a supervised environment.

Dementia extracts an enormous emotional toll and financial toll on families. Caregiving is fast becoming a major issue for baby boomers. Primary caregivers often suffer fatigue, depression, and physical illness as they wear down with the new role. Unfortunately dementia will become a bigger problem as the number of older persons on the planet increases.